Saturday, December 28, 2019

Essay on GLT task1 - 887 Words

GLT Task 1 Western Governors University What is globalization? Globalization, â€Å"refers to processes of international integration arising from the interchange of world views, products, ideas, and other aspects of culture† (Merriam-Webster, 2014). Since the 1980’s the impact of globalization has been on the rise. Western cultures are bringing about new ways of culture while indigenous people are modifying their traditional ways to western civilization. I will be discussing two non-western cultures and the effects of globalization. The two cultures that will be discussed are the Zimbabwean and Japanese cultures (Watson, 2006). McDonald’s began in 1954 in Los Angeles where it was known as just a cheap, clean,†¦show more content†¦The influence of McDonald’s making its way to Japan was direct by expanding the corporation of a successful business all over the world. Although, the start of McDonalds in Japan lead to some hesitation because it was looked upon as their culture was bei ng changed to an American way it later became a hit (Koetse, 2012). McDonald’s eventually adapted their menu to meet more of the Japanese food traditions such as rice burgers and teriyaki burgers. In addition, for desert, a green tea ice cream was launched for their taste. The seating was adapted so everyone could sit together and enjoy their meal. With the changes McDonalds has made in Japan fast food is now looked at as something trendy, even teenagers go there to study and hangout with their friends. Fast food is becoming a part of everyday life in Japan (Koetse, 2012) The second non-western culture that was impacted by globalization is the Zimbabwean culture in Africa. The changes with the economy and the liberalization of trade have affected this culture drastically (Muyale-Manenji, 1998). Prior to change, women in this culture were known as farmers and civil servants. Many of them had small businesses selling fruit and vegetables that were grown. Even young c hildren would stay out late at night to help. The impact of the globalization of trade has affected their agriculture production by putting in fertilizers and

Tuesday, December 24, 2019

Cancer #1 Essay - 842 Words

Case Study 92 Scenario R.T. is a 64-year-old man who comes to his primary care provider’s (PCP’s) office for a yearly examination. He initially reports having no new health problems; however, on further questioning, he admits to having developed some fatigue, abdominal bloating, and intermittent constipation. His nurse practitioner completes the examination, which includes a normal rectal exam with a stool positive for guaiac. Diagnostic studies include a CBC with differential, chem 14, and carcinoembryonic antigen (CEA). R.T. has not had a recent colonoscopy and is referred to a gastroenterologist for this procedure. A 5-cm mass found in the sigmoid colon confirms a diagnosis of adenocarcinoma of the colon. A referral is made for†¦show more content†¦Advanced disease Sx: pain, anorexia, weight loss, palpable abdominal / rectal mass, anemia. 6. What is a CEA? How does it relate to the diagnosis of colon cancer? Carcinoembryonic antigen (CEA) is a tumor marker that can be detected in the blood of clients with colorectal cancer. CEA level is used to estimate prognosis, monitor treatment, and detect cancer recurrence. 7. After bowel prep, R.T. is admitted to the hospital for an exploratory laparotomy, small bowel resection, and sigmoid colectomy. List at least five major potential complications for Infection (Leakage from Colon) Bleeding Blood Clots Damage to Internal Organs bulging of tissue through surgical incision colon blockage due to the formation of scar tissue incomplete joining of the reattached sections of your colon and rectum 8. After surgery, R.T. is admitted to the surgical intensive care unit (SICU) with a large abdominal dressing. The nurse rolls R.T. side to side to remove the soiled surgical linen, and the dressing becomes saturated with a large amount of serosanguineous drainage. Would the drainage be expected after abdominal surgery? Explain. Serosanguineous drainage is expected after abdominal surgery because of incision and time needed for clotting process. It is not normal if the bandage is soaked with blood, if green or yellow drainage is coming from it, or patient have black or tarry stools, or there is blood in his stool. 9. Four weeks after surgery, R.T. isShow MoreRelatedCancer Research, Section 1 ( Basics Of Cancer )1546 Words   |  7 PagesCancer Research, Section 1 (Basics of Cancer) What is cancer? Cancer is a disease where cells split uncontrollably and can invade other tissues, causing cells in the other tissues to have cancer. Where can cancer occur? Cancer can occur practically anywhere in the body. This is because cancerous cells can move anywhere in the amatomy through blood paths and lymph systems (lymph systems are lattice of organs, lymph intersections (nodes), tubes, and vessels that move lymph, a clear fluid containingRead MoreResearch Proposal: The role of perivascular macrophages in breast cancer metastasis. 1. Specific2800 Words   |  12 PagesResearch Proposal: The role of perivascular macrophages in breast cancer metastasis. 1. Specific Aims The tumour microenvironment is comprised of both malignant and non-malignant cells. Increasing evidence suggests that the fate of malignant cells is altered by the behaviour of the surrounding nonmalignant cells. Together, the diverse composition of the microenvironment, including immune cell infiltration, stromal cells and extracellular matrix, as well as nutrient and oxygen supply, shape the fateRead Moreâ€Å"Estimated to be diagnosed in 1 of every 8 women in their lifetime, breast cancer continues to1000 Words   |  4 Pagesâ€Å"Estimated to be diagnosed in 1 of every 8 women in their lifetime, breast cancer continues to present a public health concern (Haber 2322)†. Breast cancer is not biased. It affects men and women of all races and ages. â€Å"Cancer represents 30% of the burden posed by no communicable diseases in the Region of the Americas of the World Health Organization (Luciani, Silvana 640)†. In men it affects less than 1 percent of the population. Routine mammograms and checkups are not only healthy but can alsoRead MoreRing Contraction Of A Ring1556 Words   |  7 PagesRING CONTRACTION All the carbons of a ring are equivalent (a ring has no ends like an open-chain compound does),1 ring compounds can be classified as either monocyclic or polycyclic compounds. As the word â€Å"contraction† means shrinking, ring contraction can be defined as the process of shrinking larger ring compounds which are less strained into a more strained smaller ring structures. Instead of making small strained ring by chemical reaction which is very strenuous to do, ring contraction is a processRead MoreCancer : A Leading Cause Death Worldwide859 Words   |  4 PagesIntroduction â€Å"Cancer is a leading cause of death worldwide, accounting for 8.2 million deaths in 2012 (1)† (WHO, 2014). 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Due to the fact that cancer can attack anyone we are not considered to beRead MoreA Research Study On Cancer Registry History1338 Words   |  6 PagesCancer Registry History A cancer registry is an information system that collects, maintains, storages, and analyses data on people with cancer. Cancer data is important to healthcare world. Physicians, researchers, legislators, medical students, epidemiologists, and public health planners rely on this data. Researchers need it to study possible causes of cancer and doctors need it to decide the best course of treatment for their patient. The major purposes are: †¢ to establish and maintain a cancerRead More breast cancer Essay1111 Words   |  5 PagesBreast Cancer nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;Breast cancer is the most common cancer among women. The American cancer society estimates that in 2002 about 192,200 new cases of breast cancer will be diagnosed among women in the U.S. alone. Breast cancer also occurs in men. An estimated 1,500 cases will be diagnosed among men. In 2002, there will be about 40,600 deaths from breast cancer in the United States. nbsp;nbsp;nbsp;nbsp;nbsp;What is breast cancer? BreastRead MoreCancer : Etiology, Symptoms, Diagnosis, And Treatment1718 Words   |  7 Pages Colon Cancer: Etiology, Symptoms, Diagnosis, and Treatment Harold Scott Delaware Technical Community College Biology Professor Riggio November 18, 2014 Abstract A well-known fact is that cancer plays a major role in the area of health science in the United States. Cancer touches many individuals and many families across the nation. With a variety of types of cancer as well as causes, symptoms, and treatments cancer is a very broad topic of research. In particular my research focuses onRead MoreHealth And Health Care Of African American1264 Words   |  6 PagesMr. Watt’s risk factors related to colon cancer? Consider all aspects of his health, his family history and his culture. There are several race traits and risk factors from African-American such as Heart Disease, Cancer, Stroke, Diabetes, and Pneumonia/Influenza. Also they have those risk factors due to cultural difference diet and exercise such as hypertension, coronary artery disease, stroke, end stage renal disease, dementia, diabetes, and certain cancers. Especially, diabetes has more frequency

Thursday, December 19, 2019

The Book Of Mice And Men By John Steinbeck - 785 Words

Monica Soto Boloyan Thorne Humanities March 2 2016 The author of the book Of Mice Men, John Steinbeck, showed one important theme throughout the entire book. The theme the author showed most was the nature of loneliness. Steinbeck wants the reader to consider the theme of loneliness for many reasons. First, he wants us to know how people suffered through lonesome during the Great Depression era where many workers were migrating and looking for a job. The author placed the setting in a city in California named Soledad, which means ‘Solitude’ in Spanish. Also, he illustrated loneliness by including a card game called ‘Solitaire’ meaning by one’s self. Throughout the book, Steinbeck uses many characters to show loneliness. One of those characters is Crooks. Crooks suffers from extreme loneliness. Crooks lives in a bunkhouse where he is surrounded by many racist men that spend their time discriminating him just for being black. He lives by himself because the other workers won’t let him be with them. â€Å" I ain’t wanted in the bunkhouse,† â€Å" Why ain’t you wanted?† â€Å"† Cause I’m black. They play cards in there because I’m black.† (Steinbeck p.g 68) Also, Crooks admitted himself that he’s lonely. â€Å"A guy needs somebody -- to be near him.† â€Å" A guy goes nuts if he ain’t got nobody. Don’t make no difference who the guy is, long’s he’s with you. (Steinbeck p.g 72) In this quote, Crooks is telling Lennie that as long as you re with someone doesn’t matter who it is,Show MoreRelatedDiscrimination in the Book â⠂¬Å"Of Mice and Men† by John Steinbeck1451 Words   |  6 PagesDiscrimination was one of the issues that caused conflict in the novel â€Å"Of Mice and Men† by John Steinbeck. One example of discrimination in the novel comes in the form of racial discrimination against Crooks, as he is an African American. Another example of discrimination is gender discrimination against Curley’s wife. Finally, there is discrimination against mentally disabled people, which is evident in Lennie’s character. The ranch hands actions and conversations demonstrated the racial discriminationRead MoreOf Mice and Men. The question is how does John Steinbeck tackle social issues in the novel through the use of Crooks. Includes direct quotations from the book.782 Words   |  2 PagesOf Mice and Men In the novel, Of Mice and Men, the author, John Steinbeck, takes a strong stance against many social issues. Steinbeck voices his opinions on controversial rights such as women s rights and the treatment of migrant workers. One of the main points that Steinbeck addresses is his dislike for the treatment of African-Americans. He expresses his views through the hardship and turmoil of Crooks, the only African-American character in the novel. Crooks is looked down upon by his peersRead MoreJohn Steinbeck s Of Mice And Men1319 Words   |  6 PagesBryann Cervantes AP English IV Mrs. Batey Of Mice and Men To most, John Steinbeck’s Of Mice and Men is a revered novel on racial segregation in the United States. This text has been remarkably controversial because of the way it deals with difficult issues regarding race and the American dream; however, despite its disputable history, it is an incredibly important book that is used to study many aspects of race relations in the United States in the early to mid twentieth century, more specificallyRead More John Steinbeck Essay1174 Words   |  5 PagesJohn Steinbeck A novelist is someone who writes novels, or writes a fancy work of fiction which often has a complicated plot, many major and minor characters, a significant theme, and several varied settings. A novelist will use literary devices such as characterization, tone, symbolism, imagery, and figurative language. John Steinbeck, an American novelist, uses many literary devices such as metaphors, similes, imagery, and figurative language along with excellent descriptive words to developRead MoreSteinbeck’s Quest for Friendship, Dreams, and Personality in Of Mice and Men1742 Words   |  7 PagesCurly and Lennie, two men that traveled together everywhere they went. In Of Mice and Men, John Steinbeck describes friendship, dreams, and personality to describe Lennie and Curly adventures. Steinbeck believed that friendship was important. Lennie knows that George will always have his back, although Lennie cannot protect George he feels like he can (Steinbeck 14). Even though George says, he does not want Lennie with him; he does not want to leave him by himself (Steinbeck 13). When Lennie andRead MoreJohn Steinbecks Greatest Accomplishments973 Words   |  4 PagesJohn Steinbeck, born in 1902 in Salinas California to John Ernst and Olive Hamilton Steinbeck, became one of the greatest American writers of his century. Growing up Steinbeck read vigorously and was fascinated by Sir Thomas Malory’s Morte D’Arthur. It was Malory’s Morte D’Arthur that influenced Steinbeck for the rest of his life. Steinbeck graduated from Salinas High School in 1919 and attended Stanford University. He took courses in science and particularly became interested in marine biology.Read MoreOf Mice and Men Argumentative Essay1115 Words   |  5 PagesEssay Prompt: Jo hn Steinbeck’s novel, Of Mice and Men, has a controversial history. It has been repeatedly banned by school boards. Why might this book have been banned? Is such an action justified? In a five-paragraph essay, take a position for or against banning this novel. Use your three body paragraphs to develop each of three reasons for or against banning the novel. The Lost Portion of Human Society Right from the beginning of human civilization, books had become the vital flame that ignitedRead MoreAmerica Is Home To Many Great Writers Whom Come Different1709 Words   |  7 PagesAmerica is home to many great writers whom come different backgrounds. American authors like John Steinbeck who add biographical elements into their pieces of writing. John Steinbeck, one of the most honorable authors of time, is known for receiving Nobel Prize, California commonwealth club medal, Pulitzer Prize, and other great accomplishments towards publishing sixteen novels. Steinbeck’s realist style of writing and life experiences impacting his life show the reader he’s been through a lot inRead MoreAnalysis Of John Steinbeck s The Crucible 1074 Words   |  5 Pages Dylon Morrison Mr. Briggs 5 December 2014 Word Count: 978 John Steinbeck John Steinbeck was born on February 27, 1902 in Salinas, California. John decided to be a writer at the very young age of fourteen. â€Å"John used to lock himself in his bedroom and to be alone and write stories and poem†(John Steinbeck Biography). John was the first in his family to have a striving desire to become a writer, his father did everything he could to keep food on the table and his mother was a former schoolRead MoreWhat Influenced John Steinbeck?. What Exactly Influenced884 Words   |  4 PagesWhat influenced John Steinbeck? What exactly influenced Steinbeck’s writings? Was it his background, his past, or was it the way he grew up and learned. There are many factors that come into play when trying to depict what exactly influenced an author. A lot of people believe that he was heavily influenced by California, where he lived. As many as nine of his works were proven to be based off of some part of california life in his time. But not all of his inspiration could simply come from California

Monday, December 16, 2019

Treatment Of Class Ii Malocclusion Health And Social Care Essay Free Essays

string(72) " in the early intervention period of Class II Division I malocclusions\." Functional contraptions such as Bionator have been used to handle Class II malocclusion in kids. Multi-P is a freshly developed contraption engineered for early intervention of alveolar consonant and skeletal anomalousnesss. The intent of this survey was to compare the skeletal, dental and soft tissue effects of Bionator contraptions with Multi-P contraptions in the intervention of Class II malocclusion. We will write a custom essay sample on Treatment Of Class Ii Malocclusion Health And Social Care Essay or any similar topic only for you Order Now Subjects and methods: 45 category II kids were chosen and indiscriminately assigned to either the Bionator or Multi-P intervention group. After excepting 13 patients from the survey, 21 patients in Bionator and 11 patients in Multi-P group have participated in the survey. Lateral cephalograms were analyzed at the start of intervention ( To ) and at the terminal of contraption therapy ( T1 ) to measure the soft and difficult tissue alterations in both groups. The mated t.test and Leven ‘s trial were used for statistical analysis. Consequences: Decrease of ANB angle was observed in both intervention groups. The Bionator group underwent insignificant greater inframaxillary promotion as measured by the SNB angle. ( p= 0.737 ) The inframaxillary plane angle increased insignificantly in both groups. ( p A ; gt ; 0.05 ) The disposition of upper incisors decreased significantly in Multi-P group. ( p= 0.042 ) Both lips showed a inclination toward bulge relation to the E. line and S. line in both groups. Decision: Both contraptions are effectual curative agencies for category II intervention associated with inframaxillary lack and may take to standardization of the dentoskeletal parametric quantities at the terminal of the intervention. Keywords: Bionator, Multi-P, Class II malocclusion Comparative survey of the Bionator and Multi- P contraptions in the intervention of Class II malocclusion: A cephalometric survey Introduction Class II malocclusion is a skeletal disagreement that may be caused by maxillary prognathism, inframaxillary retrognathism or both conditions. 1 There are many different methods and contraptions for rectifying Class II jobs. 2 For many old ages functional contraptions have been used successfully to handle Class II Division 1 malocclusions in kids. These devices correct a important abnormalcy in the relationship between upper and lower jaws.3,4,5 Many orthodontists prefer utilizing functional contraptions as the first phase of intervention in pre-pubertal stage which can bring forth early alterations in the growing pattern1. In immature grownups, fixed functional contraptions are a intervention option to extraction therapy. 6 Functional contraptions can increase facial height7 and besides anterior arch length, bespeaking a bulge of incisors, particularly in the lower arch.8 The benefits of early intervention in Class II Division 1 malocclusion are evident: optimum wellness and map, su perior facial esthetics, fewer extractions, a decrease in continuance and troubles of subsequent therapies, fewer intervention hazards, consistent and predictable riddance of stage II intervention, and improved patient self-pride. 1, 9 Bionator is one of the most normally used contraptions for the functional intervention of Class II Division 1 malocclusion associated with inframaxillary retrusion.3,4,10 The effects of this device are known to be similar to those of other functional contraptions. Most surveies have reported that the Bionator is effectual in the intervention of mild to chair skeletal Class II malocclusions in patients with assorted teething. Ahn et Al. stated sing to proper patient choice, Bionator contraption can bring forth clinically stable and favorable results.5 Several probes conducted to place both the dentoalveolar and skeletal effects of this appliance.3,4,5,10 The dentoalveolar alterations consist of maxillary incisor abjuration and uprighting, associated with proclination of the lower incisors.11 An addition in inframaxillary molar eruption caused by accommodations on the eruption aspects of the contraption has been documented every bit good. Although no skeletal alteration has been found for the upper jaw, a favorable addition in entire inframaxillary length has been described systematically in patients treated with Bionator.12 The skeletal alterations associated with functional contraptions have important effects on the soft tissues, chiefly dwelling of alterations in the perpendicular dimensions of the face and place of the lips.4,13 Although the consequence of Bionator on soft tissue profile is still questionable.14,15 Overall cephalometric marks demonstrate the effectivity of Bionator functional intervention of skeletal Class II inharmoniousness such as: addition in ramus tallness, addition in entire inframaxillary length, gap of the gonial angle, posterior rotary motion of the condylar line in relation to the mandidbular line and backward supplanting of the condylar caput in relation to the mention system.10,12, 16 Harmonizing to De Almeida et Al. Binoator and Frankel showed statistically important additions in inframaxillary growing and inframaxillary bulge, where there were greater additions in patients treated with Bionator. In add-on Bionator caused a greater addition in posterior facial height.17 Jena et Al. concluded that Twin-block and Bionator were effectual in rectifying molar relationships and cut downing overjet in Class II Division 1 malocclusion topics. However, the Twin-block was more efficient than the Bionator.18 Multi-P ( RMO Europe, Strabourg, France ) , which launched in Europe in 2005 in Paris, is a freshly developed contraption engineered for early intervention of alveolar consonant and skeletal anomalousnesss. ( Figure 1 ) This contraption is manufactured in silicone for improved patient comfort and its high vestibular borders cause effectual counsel for dentition. Multi-P is sterilizable in sterilizers and may be disinfected in boiling H2O. One of the advantages of Multi-P is the fact that the fiction of this contraption which is clinically clip consuming ( for feeling and accommodation ) and laboratory procedures would be omitted and it can be delivered to the patient instantly after choice of the proper size. Besides flexibleness of the Multi-P might assist in alining and grading of crowded dentitions during skeletal corrections. One of its indicants is horizontal disagreements but there is no survey about effectivity of Multi-P in intervention of skeletal category II malocclusions.1 9 However, effectual interventions with similar contraptions such as eruption counsel appliance-Nite-Guide ® in kids have been reported in old studies.20,21,22 The intent of this clinical survey was to compare the skeletal, dental and soft tissue effects of Bionator contraptions with Multi-P contraptions on the skeletal and dentoalveolar constructions in the early intervention period of Class II Division I malocclusions. You read "Treatment Of Class Ii Malocclusion Health And Social Care Essay" in category "Essay examples" Subjects and methods This Randomized Clinical Trial survey was designed to measure the skeletal, dentoalveolar, and soft tissue effects of category II rectification with 2 intervention modes utilizing cephalographs of the patients. Treatment protocol consisted of category II rectification by Bionator or Multi-P contraption followed by about 2 old ages of fixed contraption therapy to polish occlusion. At first, the survey was reviewed and approved by the Human Ethics Review Committee of the Faculty of Dentistry, †¦ . University of Medical Sciences. Informed consent was obtained from all parents to let their kids to take part in the survey. Sample: Inclusion standards in this research comprised category II skeletal relationship ( clinical scrutiny of profile by an adept orthodontist, ANB angle A ; gt ; 5 A ; deg ; , SNB angle A ; lt ; 78 A ; deg ; , Wits assessment A ; gt ; 0, Facial angle A ; lt ; 95 A ; deg ; and Overjet A ; gt ; 5 millimeter, Class II grinder relationship, about optimum inframaxillary plane angle ( GoGn/SN= 32 ± 20 ) , no lasting dentitions extracted before or during intervention, good quality radiogram with equal landmark visual image taken earlier intervention ( T0 ) and after intervention ( T1 ) and the age of 9-12 old ages ( misss: 9-11 old ages old and boys: 10-12 old ages old ) . The patients who had all of the including standards were entered the survey. Exclusion standards comprised IMPA more than 90 grades, un-cooperation, retroclination of upper incisors and history of orthodontic intervention. The finding of sample size was accomplished by the undermentioned expression with a significance degree of 0.05, a power degree of 0.80 with a common criterion divergence ( Sp ) = 0.28. The minimal sample size for this survey was 11 in each group. Randomization process: The category II kids were chosen from the patients of a individual orthodontic pattern who go toing the section of orthodontias, †¦ . university of medical scientific disciplines. They were indiscriminately assigned to either the Bionator or Multi-P intervention group for the first stage of the orthodontic intervention. Randomization was accomplished by the research worker by utilizing a tabular array of random Numberss. If the figure was even, the patient was assigned to the Bionator group and if the figure was uneven, the patient was assigned to the Multi-P group. Therapy: Initially, 45 patients were in Bionator and Multi-P group. 13 patients ( 9 in Bionator group and 4 in Multi-P group ) were eliminated from the survey because of the patients ‘ hapless cooperation, excessively much missed assignments and hapless quality of radiographic images and their contraptions were changed to duplicate block. The research workers encouraged the kids before and during intervention to better the cooperation but if clinical scrutiny ( deficiency of posterior unfastened bite and no alteration in overjet ) and household study proved un-cooperation of the patient, that topic was excluded from the survey. After excepting 13 patients from the survey, the concluding size of sample was 21 patients ( 7 males and 14 females ) in Bionator and 11 patients ( 5 males and 6 females ) in Multi-P group. Before intervention oncoming, sidelong cephalographs were taken for all patients ( T0 ) . All patients were prepared for functional therapy by a primary maxillary removable contraption which contains cross enlargement prison guard and springs ( if needed ) . The enlargement was continued until no posterior cross-bite inclination observed during inframaxillary promotion. After this stage, for readying of working bite, border to inch incisors relationship ( if overjet was non more than 4-6 millimeter, and if it was more than 4-6 millimeter, progressive promotion was accomplished ) and 3-4 millimeter bite opening between cardinal incisors were considered. The Bionator contraptions were made by research lab procedures and fabricated in the same research lab. The Multi-P contraptions were provided by its maker in prefabricated signifiers with different sizes. Appropriate size was selected and delivered instantly harmonizing to patients characters. Multi-P is a flexible silicone-based contraption and has no wire constituent. All patients were instructed to utilize both contraptions full clip except for mastication, tooth brushing and contact athleticss. During intervention period the patients were checked by one clinician every 4-6 hebdomads. After 6 months of functional therapy and after accomplishing a normal overjet ( 2-3 millimeter ) , intervention with functional contraption was terminated and post-treatment sidelong cephalogram ( T1 ) was taken in the same radiology centre with the same fortunes. After the first stage of treatment/observation period, orthodontic intervention with fixed contraptions was initiated. Cephalometric analysis: Landmarks were recorded on an 8*4 inch sheet of 0.003-inch flatness, acetate following paper. Linear and angular caput movie measurings were performed with the 0.5 millimeter and 0.5 grades accuracy severally. The additive roentgenographic expansion of caput movies was non considered. All the tracings and measurings were accomplished by one occupant of orthodontias ( S.H ) . This occupant and the operator who preformed statistical analysis were blinded to which group each patient belonged. The soft and difficult tissue alterations were evaluated in all groups on standardised sidelong cephalograms. Cephalometric standards that were compared between two intervention attacks before and after intervention are: ANB angle, SNB angle, Wits assessment, overjet, overbite, N-Menton, inframaxillary plane angle ( SN/ Mand. plane ) , IMPA angle, maxillary incisors to SN and lips ( upper and lower ) distances to E. line and S. line. If after 6 months no betterment with contraption was observed the patient was excluded from this survey and another common contraption was used. Statistical analysis: All measurings were tested for group differences with regard to T0 ­ and T1 values and T0-T1 ( difference ) values. The comparing of the average values from the beginning and the terminal of the survey in each group ( intra-group comparing ) were made by the usage of a mated t. trial. The comparing of those average values and differences of pre-and post-treatment values between the groups ( inter-group comparings ) were analyzed statistically by the Leven ‘s trial. The degree of significance used was P A ; lt ; 0.05. Consequences The average pre- intervention age was 11.17  ±1.354 old ages for the Bionator group and 10.55  ±1.753 old ages for the Multi-P group. The average age of patients in both groups was non statistically different. ( p= 0.247 ) The mean intervention continuance was 10.48  ± 4.191 months for the Bionator patients and 14.09  ± 4.036 months for the Multi-P patients. The continuance of intervention with Multi-P was significantly longer than that of Bionator. ( p= 0.026 ) During intervention period the patients in both groups were examined clinically every 4-6 hebdomads. The Bionator group and the Multi-P group were really similar at the start of intervention. They did non demo any differences with the exclusion of overjet and upper incisor disposition which were more in the Multi-P group. ( p A ; lt ; 0.05 ) Skeletal alterations: Decrease in the anteroposterior apical base disagreement via an angular appraisal of ANB angle was observed in both intervention groups ( Bionator = 0.857o and Multi-p = 1.727 ) . These decreases were statistically important in both groups ( P A ; lt ; 0.05 ) nevertheless there was no important difference between two groups. ( p= 0.094 ) SNB angle increased in Bionator group ( 1.3o ) and Multi-P group ( 1.1o ) . Although these alterations were important ( p A ; lt ; 0.05 ) , there was no important difference in both groups in footings of SNB alterations. ( p= 0.737 ) The Bionator group underwent insignificant greater inframaxillary promotion as measured by the SNB angle. At the terminal of the intervention, a important lessening in the overjet and overbite was seen in both groups. ( p A ; lt ; 0.05 ) The additive distance of N- Menton was more increased in Bionator group ( 6.1mm ) than in Multi-P group ( 5.3 millimeter ) . ( p= 0.000 ) . Overall the inframaxillary plane angle ( SN/ Mand. plane ) increased insignificantly in both groups during the survey. ( p A ; gt ; 0.05 ) The two groups showed similar increasing of this angle. ( p= 0.18 ) Dentoalveolar alterations: The disposition of lower incisors showed an undistinguished addition in Bionator group ( 0.7o and p= 0.505 ) and an undistinguished lessening in Multi-P group ( 0.2o and p= 0.810 ) . There was statistically important difference in both groups ( p= 0.014 ) in footings of alterations in IMPA. A important lessening in the disposition of upper incisors ( U1 to SN ) was seen in Multi-P group ( 2.9o and p= 0.042 ) , But in Bionator group the disposition of upper incisors was increased ( 0.4o and p= 0.723 ) . However, these alterations in the dispositions of upper incisors were non significantly different between two groups. ( p= 0.076 ) Figure 2 shows the superimposition of average important dentoskeletal alterations after intervention by Bionator and Multi-P contraptions. Soft tissue alterations: The overall alterations in soft tissue profile were similar between the 2 groups. Both upper and lower lips showed a inclination toward bulge relation to the E. line and S. line in both groups. ( Table 1 ) Discussion Functional contraptions can promote the forward growing of a retrusive or under-developed lower jaw in category II malocclusions. These contraptions hold the mandible in a protrusive place. By this manner, dentitions, jaws and articulations are adapted and the desired jaw place will be obtained. Therefore the curative effectivity of functional contraptions include: skeletal, dentoalveolar and soft tissue alterations that can be evaluated by cephalometric surveies. 5 In the current survey, before intervention, both groups did non demo any important differences with the exclusion of overjet and disposition of upper incisors. The impact of the likely prejudice in the consequences of the intervention is significantly reduced by the similarity of the samples ‘ characteristics.22 This survey compared the intervention effects of 2 different category II intervention modes, one protocol integrating the Bionator contraption and the other one, the Multi-P contraption for the first stage of intervention. However, it would hold been desirable to compare the information of the Bionator and Multi-P groups with longitudinal growing informations of untreated topics with category II malocclusion to extinguish possible differences in growing forms. Unfortunately, no such sample consisting a sufficient figure of topics exists24 similar to Rudzki-Janson and Noachtar survey that did non include an untreated control sample in their survey for the rating of the i ntervention effectiveness.25 Sagittal alterations: In this survey the ANB angle showed a important lessening in both of the intervention groups. This is in understanding with the consequences of Tumer et al.26 and Sidlauskas27 surveies by utilizing monoblock and twinblock in their intervention groups, severally. The bulk of category II malocclusions have a constituent of inframaxillary lack and coercing the patients to hold maps with their lower jaw forwarded, could excite inframaxillary growth.28 In this survey, the Bionator and Multi-P contraptions significantly increased the SNB angle of treated patients. Therefore both are effectual curative agencies for category II intervention associated with inframaxillary lack. In the present survey, decreased Wit ‘s assessment and overjet and besides increased SNB showed that effectual inframaxillary growing occurred in both groups. The addition of effectual inframaxillary length after functional therapy is besides supported by different studies.4,10,12,20,21,26,2 7 However, some surveies did non demo important alterations in inframaxillary length induced by functional appliances.28 The stimulation of inframaxillary growing can be shown as a ground for the lessening of ANB angle in the Bionator group, whereas in the Multi-P group the undistinguished lessening of SNA can besides be shown as an extra factor for this lessening of ANB angle. This could be concluded that Multi-P has a small consequence on the forward growing of the upper jaw. Overall, the alterations in SNA angle by intervention in both groups were non important and this might be attributed to better control of sagittal midfacial growing. This determination is besides supported by Almeida et al.12 and Barnett et al.29 and Janson et al.30 surveies which did non happen alterations in the sagittal length or place of the upper jaw after intervention with Herbst, Bionator or Fr A ; auml ; nkel contraptions. However, Antonarakis and Kiliaridis concluded that twin block contraptions seem to move on the upper jaw ( lessening in SNA ) .31 The differences may be related to the sort of contraption and wear cli p. The Multi-P group showed a greater sweetening in the forward repositioning of the mandible compared with the Bionator group, ensuing in a grater decrease in the ANB angle. Although the differences of ANB alterations between 2 groups was non statistically important ( p= 0.094 ) , but the difference might be considered clinically important ( ANB decrease was 0.8o in Bionator group and 1.7o in Multi-P group ) . A important lessening in the grade of overjet was seen in both of the intervention groups. Some writers believed that the lessening in the overjet is perfectly dependent on the dental alterations. By the retrusion of upper incisors and the bulge of lower incisors, the grade of overjet decreases.26,27 But in this survey, the alteration in the disposition of lower incisors in both groups and in the disposition of upper incisors in Bionator group were non important. ( p A ; gt ; 0.05 ) Although the upper incisors were retruded after Multi-P intervention, it seems that stimulation of manibular growing is primary cause of overjet lessening. The ground for the lessening of overjet may be related to the stimulation of the forward growing of the mandible, in add-on to the abjuration of the upper incisors.26,27 Most of the Activator surveies available in the literature study a important decrease of ANB angle during treatment.32 Harmonizing to Albers and Dermaut, these alterations are, nevertheless, within the scope of physiological growth.33 The findings of the present survey clearly indicate that important biological alterations in the occlusal relationships ( overjet and overbite ) and inframaxillary growing increases can be achieved by Bionator and besides Multi-P therapy. This is in understanding with the consequences of Faltin et Al. ‘s survey which confirmed the advantages of Bionator therapy during pubertal growing jet. In their survey Bionator caused a important betterment in the overjet ( -4.2 millimeter ) .10 Besides in our survey, the decrease of overjet in Bionator group ( 2.5  ± 2.1 millimeter ) and in Multi-P group ( 3.1  ± 1.8 millimeter ) was statistically important ( p= 0.000 ) . Additionally, forward location of condyle-glenoid pit composite which has been report ed by Wadhawan et al.34 were non considered in this survey. Alveolar consonant: It is clear that a response to the anterior supplanting of the mandible occurs within the dental arch. The force returning the mandible to its original place causes retroclination of upper incisors and proclination of lower incisors.26,27 In the present survey, the angle between sella-nasion plane and the maxillary incisors increased in Bionator group insignificantly and decreased in Multi-P significantly. However, the two groups had no important difference in footings of alteration in upper incisor disposition. ( p= 0.076 ) In the Multi-P group, upper incisors demonstrated a greater grade of retrusion, nevertheless, within the Bionator group, the lower incisors showed a little and undistinguished grade of proclination. Tumer et Al. found that the disposition of lower incisors increased and the disposition of upper incisors decreased in monoblock and twin- block groups.26 In this survey Bionator caused bulge of lower incisors but Multi-P caused retrusion of lower incisors. Faltin et Al. ‘s topics who used Bionator contraptions when they were at the extremum of the growing speed showed important dentoalveolar promotion of the lower dentition in a mesial direction.10 These differences might be attributed to different contraption designs and have oning protocols. Sometimes cresting of the inframaxillary incisors are recommended to forestall flaring of these dentitions during Activator treatment.34,35 However, the contraption design used in the present survey did non include any capping of the lower incisors. Soft tissue: In the present survey the distances between upper lip to E. line and S. line were decreased in both groups. The upper lip protracted comparative to E. line and S. line in both groups but the upper incisors retracted in Multi-P group. Sharma and Lee did non happen a important alteration in upper lip landmarks after intervention with duplicate block and mini-block appliances.36 In Varlik et Al. ‘s study37 a lessening in 1-SN angle indicated important maxillary incisor abjuration by Activator and Twin block. However, soft tissue points related to the upper lip did non uncover a alteration relation to the perpendicular mention line. This might be attributed to the fact that incisor abjuration was accomplished largely by abjuration of the incisal border, with a little backward supplanting of the cervical point. Probably this tipping motion resulted in less alterations in the upper lip.37 Upper lip version to the alterations of incisors disposition is still controversial , Kasai et Al. 38 and Ramos et al.39 reported a mean ratio for maxillary incisor abjuration to upper lip abjuration of 2.38:1  ± 1.67 38, and 1:0.70  ± 0.05,39 severally. These surveies used additive measuring to find positional alterations of the incisors. The intent of utilizing the E. line and S. line as the mentions was non to quantify the alterations but to find whether a desirable lip relationship was achieved when the alteration in soft tissue pogonion was considered. 37 After intervention the average values of the upper lip to E and S lines in both contraption groups were really near to its normal values. ( -3.14 and 0.333 in Bionator and -1.591 and 0.909 in Multi-P severally ) In this survey, the place of the lower lip had no important alteration in both groups. Although decrease of the overjet can ensue in the uncurling of the lower lip, which in bend can take to a important addition in the labiomental angle. 37 Duration and age: In this survey the mean intervention continuance was 10.48  ± 4.191 months for the Bionator patients and 14.09  ± 4.036 months for the Multi-P patients. Although the continuance of intervention was statistically different in two groups, the 4 months difference might non be clinically different. In this survey, skeletal adulthood was non considered. The skeletal adulthood of topics was non evaluated in the Baltromejus et Al. ‘s survey, and merely age- related comparings were performed.24 However Faltin et Al. used growing phases in the cervical vertebrae for rating of skeletal maturity.10 Besides basic differences in the physiologic condylar / inframaxillary growing form between the Bionator and Multi-P were non considered in this survey. Vertical: By rating of alterations in SN/ Mand. Plane, N-Me and overbite, it can be concluded that in both groups of this survey the anterior facial tallness increased during intervention. The increased facial tallness by the usage of different functional contraptions has been shown in many studies.12,26 In Baltromejus et Al. ‘s survey, they found a strong perpendicular condylar growing stimulation and caudal supplanting of mentum induced by Activator therapy. This might be due to the intermittent forces generated by the Activator.24 In the survey of Baccetti et Al. the patients treated by twin block showed gap of the gonial angle.40 The trimming of the functional contraption leting the eruption of grinder and bicuspids might hold contributed to a perpendicular jaw development.24 The increased facial tallness during intervention in our survey showed that the Bionator and Multi-P contraptions are more favorable picks in patient with short facial tallness. This is in understanding with the consequences of Baltromejus et Al. which stated that hypo-divergent topics respond more favorably to Activator intervention than hyper-divergent subjects.24 In this survey, both groups showed increased N-Menton distance and Bionator caused greater addition in facial tallness. This might be attributed to the trimming of the posterior acrylic rosin in Bionator contraption which is impossible in Multi-P contraption. Paring the inferior boundary line of the posterior bite blocks allows the clinician to ease the eruption of the posterior teething in patients with a short lower anterior facial tallness and an accentuated curve of Spee.23 It must be noted that lessening in overbite occurred in both groups which showed the effects of both contraptions on perpendicular dimension. When the alterations in the two intervention groups were evaluated, the measurings which revealed statistically important differences are shown in Table 2. The most marked intervention alterations were about 2-6 millimeter ( in Wit ‘s, overjet and N-menton ) . This difference might look of small importance, nevertheless, harmonizing to profile surveies, a alteration of a few millimeters in one characteristic can change the aesthetics of the remainder of the face.41 Relatively high standard divergences of the values of the intervention alterations reflected a big fluctuation in the single patient responses. The stableness of the consequences achieved by functional contraption therapy has been a major concern. Continued skeletal growing can impact the skeletal and alveolar consonant alterations which could ensue in soft tissue alternations. For this ground efficient orthopedic keeping should be used. 37 The contraptions were re-evaluated after 10-14 months. Longer-term follow- up would be valuable. Besides, informations sing the long- term results of Multi-P therapy recommended for a unequivocal assessment of the stableness of the really favorable short- term dentoskeletal alterations. The comparatively little figure of patients involved in this survey may hold been excessively few to foreground any differences between the Multi-P and Bionator. Although there was an equal figure of possible patients, several patients were un-cooperative and some patients had uncomplete records. Besides clip and equipment handiness were of import confining factors. Overall the Bionator is comparatively susceptible to breakage but the flexible nature of Multi-P decreases this occurrence. The Bionator is constructed in all Persian orthodontic research labs and its cost is about half or one- tierce of the Multi-P contraptions. The Multi-P contraption which is prefabricated demands a small chair-side clip of the clinician but the Bionator needs fiction of building bite by the clinician which in some patients stopping points for a long chair-side clip. From a clinical point of position, the Bionator requires more accommodation than the Multi-P contraption. The patients ‘ perceptual experiences of their contraptions might be utile to clinicians but this was non considered in this survey. Decision The findings of the present survey on Multi-P therapy in category II patients indicate that this intervention protocol is effectual. In this survey, the Bionator and Multi-P contraptions increased significantly the SNB angle of treated patients. Therefore both are effectual curative agencies for category II intervention associated with inframaxillary lack and they can take to standardization of the dentoskeletal parametric quantities at the terminal of the intervention. How to cite Treatment Of Class Ii Malocclusion Health And Social Care Essay, Essay examples

Wednesday, December 11, 2019

Today the Mexican agriculture is in transition. Th Essay Example For Students

Today the Mexican agriculture is in transition. Th Essay is sector that was stagnant over the past two and a half decades, has become the subject of government initiatives aimed at its modernization within a larger national context of economic reform. This essay will look at the challenges of the agricultural sector and state its new role in the Mexicans economy. The Mexico agricultural system exports fruits and vegetables, beer and tequila, seafood and cattle, and imports grains, oilseeds and animal products, some of these products will be discussed also. First off the Mexican government has started to promote exports in their country and has been trying to make agriculture competitive. This has developed new programs for financing agriculture and capitalizing the sector. The government has been also trying to protect the countrys natural resources and trying to promote alternatives in farming. In new sweeping changes the Mexico government has deregulated markets, lowered internal trade barriers, and eliminated red tape for investors and government intervention. All of this has added to the economy of Mexico and improved the agriculture system from decades ago. Mexico has 39 million hectares suitable for forests, 125 million hectares suitable for cattle raising, 30 million hectares suitable for crops and 10 million hectares of irrigated arable land, which add to promote this country for future use in this industry. These points are positive for Mexico for future economic benefit and agricultural improvements. Mexico is one of the worlds largest exporters of fruits and vegetables, with value of exports representing 20 percent of the 6. 14 billion-dollar world trade. The country currently holds one of the top places in the worldwide fruit production and has low production costs. The North American market absorbs 90 percent of total Mexican fruit and vegetable exports, which in 1990, amounted to approximately $990 million dollars (U.S.). Tomatoes are the principal vegetable produced and exported, with production added to 3 percent of the total agricultural output. Tomatoes account for 31.8 percent of vegetable exports. Mexico ranks second in the world tomato market. The recent privatization of sugar mills in Mexico has made the national sugar industry a competitive activity. The new pricing system, including sliding tariff scale, has created a horizon for price stability and protests the industry for international market. The tabacco and coffee sector is very popular and a very big industry in Mexico. The Mexican coffee industry ranks fourth in the world. Beef is a very important product in the producing sector of the Mexican economy. The beef industry is on the growth with a 9 percent increase every year for the last 6 years. Pork production is another major livestock industry. In 1991, 28 percent of Mexicos total meat came from pork. Pork is the most ate meat in Mexico, with a 5 percent increase in pork production between 1990-1991. Sales of pork products, such as sausage and cold meats have increased as they make up an important part of the average Mexicans diet. The strengths of the Mexican agricultural system is the fruit and vegetables production are up to world class standards and Mexico has different types of climates which allow to produce almost any kind of agricultural product. They also have a large fishery potential due to the vast coastline. The weaknesses of the Mexican agricultural system is lack of modern technology, lack of local manufacturing in equipment and lack of capabilities of new product development. The flower industry has been a new economic activity, which has grown in the years. The value of flower exports has grown from 1 billion dollars in 1982 to 25 million dollars in 1989. .u1b39be84ea5810c666d057ffa895e59d , .u1b39be84ea5810c666d057ffa895e59d .postImageUrl , .u1b39be84ea5810c666d057ffa895e59d .centered-text-area { min-height: 80px; position: relative; } .u1b39be84ea5810c666d057ffa895e59d , .u1b39be84ea5810c666d057ffa895e59d:hover , .u1b39be84ea5810c666d057ffa895e59d:visited , .u1b39be84ea5810c666d057ffa895e59d:active { border:0!important; } .u1b39be84ea5810c666d057ffa895e59d .clearfix:after { content: ""; display: table; clear: both; } .u1b39be84ea5810c666d057ffa895e59d { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u1b39be84ea5810c666d057ffa895e59d:active , .u1b39be84ea5810c666d057ffa895e59d:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u1b39be84ea5810c666d057ffa895e59d .centered-text-area { width: 100%; position: relative ; } .u1b39be84ea5810c666d057ffa895e59d .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u1b39be84ea5810c666d057ffa895e59d .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u1b39be84ea5810c666d057ffa895e59d .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u1b39be84ea5810c666d057ffa895e59d:hover .ctaButton { background-color: #34495E!important; } .u1b39be84ea5810c666d057ffa895e59d .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u1b39be84ea5810c666d057ffa895e59d .u1b39be84ea5810c666d057ffa895e59d-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u1b39be84ea5810c666d057ffa895e59d:after { content: ""; display: block; clear: both; } READ: Christopher Columbus2 Essay The exports to the major markets consist of mainly of carnations and roses. Research in Mexico in the 1950s and 1960s led to the development of the high yielding varieties of wheat and rice that launched the Green Revolution. The reason for these high yielding varieties and its success was because of water, fertilizers, machinery and availability to it. The farmers in Mexico that had access to this progressed, also with the help of access to water and transport. This can help produced food and security for a very increasing population in Mexico. Fertilizer use is up in Mexico from just around 40-50 in the late 1970s to 70 kilograms per hectare of cropland in early 1990s, for the average annual fertilizer use. This shows a reason for increase growth in food productions and soil conditions in Mexico. NAFTA was expected to enhance the division of labour between the United States, Canada and Mexico in agriculture. The United States would export more grains, oilseeds, .

Sunday, December 8, 2019

Enzyme lab free essay sample

Introduction Enzymes are the ultimate catalysts of living things. Enzymes are made of proteins which are structured and directed by amino acids chains. Enzymes attract and fit substrate molecules to an active site. The active site binds the substrate molecules covalently to enzyme forming an enzyme-substrate complex, which catalyzes the substrate molecule into a product. Enzymes have the capability to break or build compounds which keep cell systems functioning. For example, our digestive tract has catabolic enzymes which break apart food for storage and reuse. Our lab experiment studied the relationship of benzoquinone production when altering the pH and temperature of the reaction, as well as enzyme and substrate concentrations. We used a Spec 20 to evaluate absorbance at 540 nm. Absorbance represents rate of product formation. We tested the substrate catechol and the enzyme catacholase and recorded the product benzoquinone. The objective was to identify the optimal conditions for the enzyme catacholase. I predicted that the reaction rate will rise with increasing enzyme concentrations until an optimal reaction rate is attained. This is because there are only so many substrates that need to react with the active sites on the enzymes. Once this equilibrium is reached the graph will stabilize and remain constant. I predicted that the reaction rate will increase with increasing substrate concentrations until an optimal point where there aren’t enough active sites on the enzymes to accommodate the influx of substrate molecules. At this point the graph will reach equilibrium and remain constant. I predicted that heat would accelerate the reaction because if molecules have high kinetic energy their motions will become increasingly rapid. An incline in the graph will be evident but a decline will also occur because proteins denature at high temperatures. The enzyme will lose its shape and thus its work function will diminish, like an overheated car. This graph should   resemble a pyramid. I predicted that the most acidic and basic environments would have a low level of reaction and that neutral pH will produce the greatest level of reaction. Living systems operate in a certain cell environment, pH levels vary in hydrogen ion concentrations. I presumed that the potato would need a neutral pH solvent because most enzymes generally function at neutral pH levels. This graph will resemble a bell curve. Methods We conducted four experiments. All four test results measured benzoquinone production by a spectrophotometer at 540nm. Higher levels of absorbency means higher rates of benzoquinone production. In the first experiment we tested how enzymatic concentration will affect the level of benzoquinone production. We had four treatments all; with equal total volume, a constant substrate concentrations and varying enzyme extract concentrations (Table A.1). The enzyme-substrate complex will form and react spontaneously upon adding the extract; therefore in all experiments catacholase was added last to each test tube. We covered the four tubes with parafilm and inverted the tubes for three minutes at one minute intervals. We then recorded the absorbance. In activity B our objective is to determine if substrate concentration will affect the level of benzoquinone production. There are six treatments each have equal total volume, constant extract (enzyme) concentrations and varying substrate (catechol) concentrations (Table B.1). After amounted water and substrate is mixed the enzyme was added last. The tubes were covered with parafilm and inverted for three minutes at a one minute intervals. Once each tube has been processed for three minutes re-zero the Spec and then record the absorbance units. In activity C our objective is to test how different temperatures will affect the rate of benzoquinone production. In our four treatments each was held at a certain temperature (Table C.1). We prepared the temperate environments by; putting 100 mL of tap water with boiling chips in a beaker and on a hot plate, we placed ice into a separate beaker for an ice bath, we positioned a tube rack for room temperature test, and then placed another  beaker into a warm water bath. We measured 4 mL of catechol and 1 mL of water into all four tubes. After we covered the four tubes with parafilm and inverted followed by the incubation of tubes in their designated environments for five minutes. After five minutes we added 1 mL of potato extract (enzyme) and covered all but the boiling tube. We inverted the catacholase (to mix boiling tube we carefully stirred). After adding the enzyme we measured the temperature of each tube and then incubated them in their temperate environments for five more mi nutes. Following five minutes we prepared the Spec and recorded the absorbance. In activity D our objective was to test whether pH level would increase or decrease benzoquinone production. We added varying pH levels into four tubes based on (Table D.1). We covered the tubes with parafilm and inverted each for three minutes in one minute intervals. After three minutes we prepared the Spec and recorded each tube’s absorbance. Results and Discussion As the enzyme concentration increased, there was a solid increase in benzoquinone production (Figure A.1). My hypothesis stated that product formation would rise until a maximum was obtained. Based on the data, my results did not support my hypothesis. From this experiment I learned that the concentration of enzymes can significantly speed up reaction rate and that enzymes are versatile in that they will bind substrate molecules and catalyze at a high rates even if the substrate level is constant. This test could be improved by including more enzyme concentrations to broaden our data spectrum and perhaps then my hypothesis will be supported. As substrate concentration increased, there was an increase in absorbance followed by a plateau around 1.6 ml of catechol (Figure B.1). My hypothesis stated that product formation would rise until a maximum when absorbance would plateau because substrate molecules would outnumber enzyme active sites. Based on data gathered, results support my hypothesis because with 0.5 :1 substrate to enzyme ratio, production began to level off. From this experiment I learned that catechol concentration has a big impact because the substrate represents the workload that needs to be acted on and therefore the higher concentrations can overload enzyme workspace. If we  were to expand this experiment and include more substrate concentrations then we could assess the hypothesis more accurately to see if the enzyme reaction rate continues to remain constant when enzyme occupation is reached. Benzoquinone product formation climaxed at 52 degrees Celsius this is the optimal functioning rate, any temperature to follow will obstruct the enzyme’s function and result in decreasing levels of product formation (Figure C.1). My hypothesis stated that the enzyme will function faster with activation energy supplied from kinetic heat. But that this fast rise will subsequently be prone to a rapid decrease because once optimal temperature is breached, the tertiary structure of the enzymatic proteins will unravel into dormant amino acid chains. Our test results support my hypothesis in that there is a cone shaped graph which represents a maximum functioning level of 52 degrees Celsius. There is a rapid decline at 99.3 degrees Celsius. From this experiment we learn that enzymatic rate of product formation depends on the solution temperature. Such as the maladies fever instills, high temperature denatures proteins which disable enzymes capability to function properly. We could expand this experiment by testing different substrates other than catechol to see if this temperature relationship/pattern is applicable to other enzymatic reactions. The high acidic and basic solvents had a low reaction rate while the neutral/basic environment had the highest benzoquinone production (Figure D.1). My hypothesis stated that the graph would resemble a bell curve because most enzymes catalyze within a neutral solvent environment. Our test results support this hypothesis slightly because there was a bell shape curve, however I learned that the enzyme catacholase generates benzoquinone faster in a slightly basic environment specifically pH 8. We can expand this experiment by using other substrates (not catechol) with the same test process we can compare what kinds of substrates operate in certain pH environments. It would be interesting to find a pattern or categories in which substrate react accordingly with, for example the enzymes in our gut work in a slightly acidic microenvironment. Conclusion Enzymes help biological systems function. They induce the biochemical process by holding reactants in position and catalyzing the reaction to form the product. Catecholase, the enzyme, lowers the activation energy needed  for benzoquinone to form, which makes the chemical reaction happen much quicker. The rate of enzymatic reaction is very important to every organism’s survival. We act accordingly to ensure a stable environment in our bodies so that our metabolism and immune systems function properly. The enzyme is like a crane that transfers iron rods onto a building structure, without that mechanism the building would take forever to build! Multiple chemical reactions occur for a process to function. If the enzymes which catalyze such reactions aren’t regulated, metabolic pathways would result in chaos. The objective in this experiment was to evaluate what solute concentrations and physical environments the enzyme catacholase would function best to. We tested what enzyme and substrate concentrations and what temperature and pH levels would generate the highest reaction rates. We analyzed how these variables would effect enzyme function by measuring the rate of benzoquinone production in absorbance. We found that high enzyme concentration would increase product formation; that high substrate concentrations would plateau when no enzyme work sites are left vacant; that catacholase denatures after the optimal heat of 52 degrees Celsius; and that catacholase functions best at a pH 8 level. It is important to understand how enzymes perform the best because then we can have greater control over the maintenance of these vital systems. For example your body can become too acidic from alcohol poisoning which causes body malfunctions and ultimately a black out. In this lab I found that the enzyme catacholase worked best when enzyme concentration was greatest resulting in a positive linear graph, and that the substrate concentration would as well enhance reaction rate until 1.5mL of catechol concentration, at which point enzyme reactors are all occupied and the graph plateaus. We also can conclude that 52 degrees Celsius is catacholase’s optimal function level and that a slightly basic pH solvent is most efficent for product formation. These experiments represent a selective study based on limited solute concentrations and temperature and pH test environments. Further study on enzymatic functions can proceed by adding more substrate and enzyme concentrations, this will expand data and grant a bigger picture as to how reaction formation will continue. In relation to enzymatic environment levels we can further the temperature and pH experiments by incorporating a different solute unlike catachol to determine if any patterns of favored  microenvironments develop.

Wednesday, December 4, 2019

Our Right To Drugs Essays - Drug Control Law, Anti-psychiatry

Our Right To Drugs You might be tempted to label Thomas Szasz, author of Our Right to Drugs, The Case for a Free Market, a counter-culture hippie. However, this analysis couldn't be further from the truth. Szasz, a Professor Emeritus of Psychiatry at the State University of New York Health Science Center in Syracuse, is a major supporter of civil liberties. He sees the so-called War on Drugs as one of the worst atrocities that the American Government has perpetrated on its people. Szasz contends that the prohibition of certain drugs, including common prescription drugs, is nothing more than the government telling the people that father knows best. It is this paternalistic attitude that Szasz finds so oppressive. Mr. Szasz makes three key arguments throughout his book. First, the War on Drugs is a failure and can never succeed. It should be stopped immediately. Second, drug legalization is not a viable answer. It would only turn into another attempt by the government to control drugs and would not be any more of a free market than the current system of drug prohibition. Third, he proposes a solution. The solution is to end all drug regulation by the government; in effect, creating a free market for drugs. He doesn't stop at illicit drugs, however. He also includes prescription drugs in this solution as well. He sees the government's drug control policy as an attempt by the government to control its population, much like a parent controls his/her children. In order to get at what Mr. Szasz is saying, we must first examine his definition of what a free market is. Szasz defines the free market as the right of every competent adult to trade in goods and services. (Szasz, page 2). In other words, he is outlining a laissez-faire system of the free market. Szasz contends that the government's only role in a free market is to protect people from force and fraud and, to the maximum extent possible, abstain from participating in the production and distribution of goods and services. (Szasz, page 2). In this system of laissez-faire, the government has a very small role. According to Szasz, the government should have a passive role in any market, including the market for drugs. Once the government gives up its active role, which is represented by the war on drugs, a free market for drugs which Szasz proposes can be attained. As we delve into Mr. Szasz's first argument, we begin to see major problems with the government's War on Drugs. According to Szasz, the prohibition of drugs is a blatant violation of human rights guaranteed to American citizens by the Constitution. In order to prove his point, he equates drugs to personal property. According to the Constitution, every American citizen shall have the inalienable right to life, liberty, and property, the first two elements resting squarely on the last. (Szasz, 1). Thus, Szasz contends that because both our bodies and drugs are types of property?producing, trading in, and using drugs are property rights, and drug prohibitions constitute a deprivation of basic constitutional rights. (Szasz, 2). In other words, just like the prohibition of alcohol required a constitutional amendment, so does the prohibition of drugs. Without that amendment, the prohibition of drugs is in direct violation of the Constitution. The second argument that Szasz makes is one, surprisingly enough, against the legalization of drugs. Even though Szasz argues for a free market for drugs, this is much different from the argument that self-proclaimed drug legalizers make. According to Szasz, most proponents of drug legalization argue for what he calls Legalization as Taxation (Szasz, page 106). Ethan Nadelmann, professor of politics and public affairs at Princeton University, claims the following, Let's say we decide, okay, we're not going to legalize crack; what we will do is legalize 15-percent cocaine. . . . Yes, some people are still going to want to go to the black market. . . and buy crack. You won't be able to prevent that. But let's say 70 percent of the market will be using the legal, less potent substance. That's good, because the government taxes it, regulates it. . . . The object is to undercut the criminal element (Szasz, page 106). From this,